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Drink Alcoholic beverages or use prescription or around-the-counter medicines that comprise alcohol. Applying goods containing Liquor for the duration of procedure with acetaminophen and codeine phosphate tablets could cause you to definitely overdose and die.
Abuse of and addiction to opioids in a few persons may not be accompanied by concurrent tolerance and indicators of Actual physical dependence. On top of that, abuse of opioids can come about from the absence of addiction.
Advise individuals of the potential risk of daily life-threatening respiratory depression, together with facts that the risk is best when commencing acetaminophen and codeine phosphate tablets or when the dosage is amplified, Which it could possibly come about even at suggested dosages.
The precise system with the analgesic Homes of acetaminophen just isn't recognized but is believed to include central actions.
Respiration Problems. Codeine may possibly bring about sluggish or shallow respiration, particularly when you've got respiration complications from A different situation or get other medicines which can gradual your respiration.
See disposal information at the bottom of the area for Instructions regarding how to properly toss absent (get rid of) your unused acetaminophen and codeine phosphate tablets.
Increased Suffering Sensitivity (Hyperalgesia). Codeine could potentially cause a heightened sensitivity to suffering. It could potentially cause things that Ordinarily bring about agony to really feel additional unpleasant than standard. Codeine also can bring about allodynia. This comes about when things that Typically tend not to trigger suffering, for example wearing Eyeglasses or brushing your hair, come to be unpleasant.
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A multimodal method of ache management may improve the procedure of Long-term pain, together with guide Together with the effective tapering of the opioid analgesic [see Warnings/Withdrawal, Drug Abuse and Dependence].
Others are more likely to get critical aspect effects simply because an exceedingly significant volume of morphine is produced. If you see any of the next facet effects, it's essential to stop taking this drugs and look for fast professional medical suggestions: slow or shallow respiration, confusion, sleepiness, compact pupils, feeling or remaining sick, constipation, deficiency of hunger.
Check with your healthcare provider When the ache that you've raises, if you're feeling a lot more delicate to suffering, or When you have new discomfort right after having acetaminophen and codeine phosphate tablets.
To lessen the risk of respiratory melancholy, right dosing and titration of acetaminophen and more info codeine phosphate tablets are important [see Dosage and Administration].
Respiratory despair can happen Anytime through opioid therapy, especially when initiating and pursuing dosage boosts with acetaminophen and codeine phosphate tablets. Look at this danger when deciding upon an Original dose and when earning dose changes [see Warnings].
If concomitant use by using a CYP2D6 inhibitor is essential, evaluate the client for indications of diminished efficacy or opioid withdrawal and look at escalating the acetaminophen and codeine phosphate tablets dosage.